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Next: MC341 Group Theory Up: Year 3 Previous: MC316 Parallel and Distributed

MC320 Modelling Biological Systems


MC320 Modelling Biological Systems

Credits: 20 Convenor: Dr. M. Walmsley Semester: 1


Prerequisites: essential: MC120, MC121, MC144, MC145, MC146, MC147, MC248
Assessment: Coursework: 10% Three hour exam: 90%

Lectures: 36 Classes: 10
Tutorials: none Private Study: 104
Labs: none Seminars: none
Project: none Other: none
Total: 150

Explanation of Pre-requisites

The module requires a general mathematical background, with some knowledge of the use of Maple.

Course Description

This module uses differential equations of various kinds to describe certain problems in the biological sciences. There are particular applications to population models (including interaction between species) and epidemic models. Some new techniques concerned with coupled differential equations and partial differential equations are introduced.

Aims

The module will investigate a range of biological problems using modern mathematical tools. The aim is to indicate the applicability of mathematics to recent work in the life sciences.

Objectives

To be able to integrate simple ordinary differential equations, determine their steady states and discuss the nature of their stability.

To be able to sketch direction fields and typical solutions and make appropriate deductions concerning the biological problem under discussion.

To know how to introduce dimensionless variables.

To be able to use linear and nonlinear differential equations (usually $2\times 2$, but possibly more when discussing epidemics) to describe a given biological problem.

To know how to use the theory for $2\times 2$ autonomous systems (eigenvalues, trace and determinant of Jacobian) to determine the character of steady state solutions.

To be able to investigate the behaviour of solutions of differential equations using standard MAPLE routines to obtain direction fields and phase portraits.

To be able to make deductions concerning the biological problem from the mathematical results.

To know how to derive the diffusion equation in one and three dimensions.

To be familiar with the elementary solution and the error function solution of the 1D diffusion equation.

To be able to use solutions of the diffusion equation in modelling particular problems.

Transferable Skills

Mathematical modelling and problem solving skills, including the use of differential equations routines in Maple.

Syllabus

1.
Single species population models -- deterministic models.
2.
Phase-plane methods and qualitative solutions of systems of ordinary differential equations, with applications to predator-prey models, the Lotka-Volterra equations, the population biology of infectious diseases. Maple provides suitable tools for the investigation of problems arising in this area.

3.
Introduction to the diffusion equation and its solution with applications to particular problems.

Reading list

Background:

M.Braun, Differential Equations and Their Applications, Springer.

E. Renshaw, Modelling Biological Populations in Space and Time, CUP.

J. D. Murray, Mathematical Biology, Springer

There is no single textbook for the course and students will be referred to the above relevant texts where appropriate; for example, Braun discusses Phase-plane methods, and Renshaw includes items of interest. Murray is an advanced textbook, small parts of which are relevant to the course. All books are available in the library.

Details of Assessment

The final assessment of this module will consist of 10% coursework and 90% from a three hour examination during the January exam period. The 10% coursework contribution will be determined by students' solutions to coursework problems. The examination paper will contain 6 questions with full marks on the paper obtainable from 4 complete answers.


next up previous
Next: MC341 Group Theory Up: Year 3 Previous: MC316 Parallel and Distributed
S. J. Ambler
11/20/1999